Publication List

2020

2019

2018

2017

2016

2015

2014

2013

2012

2011

2010

2009

26. João Franco Machado, Diogo A. Sequeira, Fernanda M. Marques, Maria Fátima Minas da Piedade, Maria Villa Brito, Maria Helena Garcia, Alexandra R Fernandes, Tânia S. Morais*, “New copper(I) complexes selective for prostate cancer cells”, Dalton Trans., 2020, 49, 12273-12286. DOI:10.1039/D0DT02157A

25. Diana Fontinha, Sílvia A. Sousa, Tânia S. Morais, Miguel Prudêncio, Jorge H. Leitão, Yann Le Gal, Dominique Lorcy, Marta M. Andrade, Mariana F.G. Velho, M. Almeida, Dulce Belo, Joana F. Guerreiro, Rafaela A. L. Silva, Teresa Pinheiro, Fernanda Marques, “Gold(III) bis(dithiolene) complexes: from molecular conductors to prospective antitumor, antimicrobial and antiplasmodial agentes”, Metallomics, 2020, 12, 974-987. DOI: 10.1039/D0MT00064G.

24. João Franco Machado, Miguel Machuqueiro, Fernanda M. Marques, Maria Paula Alves Robalo, Maria Fátima Minas da Piedade, Maria Helena Garcia, João D. G. Correia, Tânia S. Morais*, “Novel “ruthenium cyclopentadienyl”-peptide conjugate complexes against human FGFR(+) breast cancer”, Dalton Trans., 2020, 49, 5974-5987. DOI: 10.1039/D0DT00955E.  

 

 

23. Catarina Bravo, Maria Paula Alves Robalo, Fernanda M. Marques, Alexandra R Fernandes, Diogo A. Sequeira, Maria Fátima Minas da Piedade, Maria Helena Garcia, Maria Villa Brito, Tânia S. Morais*, “First heterobimetallic Cu(I)−dppf complexes designed for anticancer applications: synthesis, structural characterization and cytotoxicity”, New J. of Chem., 2019, 43, 12308-12317. DOI: 10.1039/C9NJ02068C.     

22. Lurdes Gano, Teresa Pinheiro, António Pedro Matos, Francisco Tortosa, Tiago F. Jorge, Maria Salomé Gonçalves, Tânia S. Morais, Andreia Valente, Ana Isabel Tomaz, Maria Helena Garcia, Fernanda Marques, “Antitumour and Toxicity Evaluation of a Ru(II)-Cyclopentadienyl Complex in a Prostate Cancer Model by Imaging Tools”, Anti-Cancer Agents in Med. Chem.2019, 19, 1262-1275. DOI: 10.2174/1871520619666190318152726.

21. Tânia S. Morais*, Yann Jousseaume, M. Fátima M. Piedade, Catarina Roma-Rodrigues, Alexandra R. Fernandes, Fernanda Marques, Maria J. Villa de Brito, M. Helena Garcia, “Important cytotoxic and cytostatic effects of new Copper(I)-phosphane compounds with NN, NO and NS bidentate ligands”, Dalton Trans., 2018, 47, 7819-7829. DOI: 10.1039/C8DT01653D

20. João Lopes, David Alves, Tânia S. Morais*, Paulo J. Costa, M. Fátima M. Piedade, Fernanda Marques, Maria J. Villa de Brito*, M. Helena Garcia, “New copper(I) and heteronuclear copper(I)–ruthenium(II) complexes: Synthesis, structural characterization and cytotoxicity”, J. Inorg. Biochem., 2017, 169, 68-78. DOI: 10.1016/j.jinorgbio.2017.01.007

19. Nuno Mendes, Francisco Tortosa, António Matos, Fernanda Marques, Tânia S. Morais, Andreia Valente, Ana Isabel Tomaz, Fátima Gartner, M. Helena Garcia, “In vivo performance of a ruthenium cyclopentadienyl compound in an orthotopic triple negative breast cancer model”, Anti-Cancer Agents in Med. Chem., 2017, 17(1), 126 - 136. DOI: 10.2174/1871520616666160922165133

18. Tânia S. Morais, Andreia Valente, A. Isabel Tomaz, Fernanda Marques, M. Helena Garcia, “Tracking antitumor metallodrugs: promising agents with the Ru(II)and Fe(II)cyclopentadienyl scaffolds”, Future Med. Chem., 2016, 8(5), 527-544. DOI: 10.4155/fmc.16.7.

17. Mariana Fernández, Esteban Rodríguez Arce, Cynthia Sarniguet, Tânia S. Morais, Ana Isabel Tomaz, Claudio Olea Azar, Roberto Figueroa, J. Diego Maya, Andrea Medeiros, Marcelo Comini, M. Helena Garcia, Lucía Otero, Dinorah Gambino, “Novel ruthenium(II) cyclopentadienyl thiosemicarbazone compounds with antiproliferative activity on pathogenic trypanosomatid parasite”, J. Inorg. Biochem., 2015, 153, 306-314. DOI: 10.1016/j.jinorgbio.2015.06.0 18.

16. Esteban Rodrígues Arce, Cynthia Sarniguet, Tânia S. Morais, Marisol Vieites, Ana Isabel Tomaz, Andrea Medeiros, Marcelo Comini, Javier Varela, Hugo Cerecetto, Mercedes González, Fernanda Marques, M. Helena Garcia, Lucía Otero, Dinorah Gambino, “A new ruthenium cyclopentadienyl azole compound with activity on tumor cell lines and trypanosomatid parasites”, J. Coord. Chem., 2015, 68, 2923-2937. DOI: 10.1080/00958972.2015.1062480

15. Leonor Côrte-Real, Filipa Mendes, Joana Coimbra, Tânia S. Morais, Ana Isabel Tomaz, Andreia Valente, Maria Helena Garcia, Isabel Santos, Manuel P. Bicho, Fernanda Marques; “Anticancer activity of structurally related ruthenium(II) cyclopentadienyl complexes”, J. Biol. Inorg. Chem., 2014, 19, 853-867. DOI: 10.1007/s00775-014-1120-y.

14. Tânia S. Morais, Filipa C. Santos, Tiago F. Jorge, Leonor Côrte-Real, Paulo J. A. Madeira, Fernanda Marques, M. Paula Robalo, António Matos, Isabel Santos, M. Helena Garcia, “New Water-soluble Ruthenium(II) Cytotoxic Complex: Biological Activity and Cellular Distribution”, J. Inorg. Biochem., 2014, 130, 1 - 14. DOI: 10.1016/ j.jinorgbio. 2013.09.013.

13. Tânia S. Morais, Filipa C. Santos, Leonor Côrte-Real, M. Helena Garcia, “Exploring the effect of the ligand design on the interactions between [Ru(h5-C5H5)(PPh3)(N,O)][CF3SO3] complexes and Human Serum Albumin”, J. Inorg. Biochem., 2013, 129, 94 - 101. DOI: 10.1016/ j.jinorgbio. 2013.09.008.

12. Ana Cristina Gonçalves, Tânia S. Morais, M. Paula Robalo, Fernanda Marques, Fernando Avecilla, Cristina P. Matos, Isabel Santos, Ana Isabel Tomaz, M. Helena Garcia, “Important cytotoxicity of novel iron(II) cyclopentadienyl complexes with imidazole based ligands”, J. Inorg. Biochem., 2013, 129, 1 - 8. DOI: 10.1016/j.jinorgbio. 2013.07.033.

11. Susana Quintal, Tânia S. Morais, Cristina P. Matos, M. Paula Robalo, M. Fátima M. Piedade, Maria J. Villa de Brito, M. Helena Garcia, Mónica Marques, Carla Maia, Lenea Campino, João Madureira, “Synthesis, structural characterization and leishmanicidal activity evaluation of ferroncenyl N-hterocyclic compounds”, J. Organomet. Chem., 2013, 745-746, 299-311. DOI: 10.1016j/jorganchem. 2013.07.044.

10. Leonor Côrte-Real, António P. Matos, Irina Alho, Tânia S. Morais, Ana Isabel Tomaz, Maria Helena Garcia, Isabel Santos, Manuel P. Bicho, Fernanda Marques, “Cellular Uptake Mechanisms of na Antitumor Ruthenium compound: The endossomal/Lysosomal System as a Target for Anticancer Metal-Based Drugs”, Microscopy and Microanalysis, 2013, 1-9. DOI: 10.1017/S143192761300175X.

 9. Tânia S. Morais, Filipa C. Santos, Leonor Côrte-Real, Fernanda Marques, M. Paula Robalo, Paulo J. Amorim Madeira, M. Helena Garcia, “Biological activity and cellular uptake of [Ru(h5-C5H5)(PPh3)(Me2bpy)][CF3SO3]”, J. Inorg. Biochem., 2013, 122, 8-17. DOI: 10.1016j/jinorgbio.2013.01.011.

 8. Ana Isabel Tomaz, Tamás Jakush, Tânia S. Morais, Fernanda Marques, Rodrigo F. M. de Almeida, Filipa Mendes, Éva A. Enyedy, Isabel Santos, João Costa Pessoa, Tamás Kiss, M. Helena Garcia, “[RuII(h5-C5H5)(bipy)(PPh3)]+ a promising large spectrum antitumor agent: cytotoxic activity and interaction with human sérum albumin”, J. Inorg. Biochem., 2012,  117, 261 – 269. DOI: 10.1016/j.jinorgbio. 2012.06.016.

 7. Paulo J. Amorim Madeira§, Tânia S. Morais§, Tiago Silva, Pedro Florindo, M. Helena Garcia,”Gas-phase behaviour of Ru(II) cyclopentadienyl-derived complexes with N coordinated ligands by electrospray ionization mass spectrometry: fragmentation pathways and energetics”, Rapid Comm. Mass Spectrom., 2012, 26, 1675-1686. DOI: 10.1002/rcm.6276. (§ both authors contributed equally to the work)

 6. Tânia S. Morais, M. Helena Garcia, M. Paula Robalo, M. Fátima M. Piedade, M. Teresa Duarte, M. José Villa de Brito, Paulo J. Amorim Madeira, “Synthesis and structural characterization of new piano-stool ruthenium(II) complexes bearing 1-butylimidazole heteroaromatic ligand”, J. Organomet.Chem., 2012, 712, 112- 122. DOI: 10.1016/j.jorganchem.2012.04.024.

 5. Tânia S. Morais, Tiago J. L. Silva, Fernanda Marques, M. Paula Robalo, Fernando Avecilla, Paulo J. Amorim Madeira, Paulo J. G. Mendes, Isabel Santos, M. Helena Garcia, “Synthesis of organometallic ruthenium(II) complexes with strong activity against several human cancer cell lines”, J. Inorg. Biochem., 2012, 114, 65-74. DOI: 10.1016/j.jinorgbio.2012.04.014.

 4. M. Helena Garcia, Tânia S. Morais, Andreia Valente, M. Paula Robalo, Mercè Font-Bardia, Teresa Calvet, Julia Lorenzo, Francesc X. Avilés, “DNA interaction and cytotocixity studies of new ruthenium(II) cyclopentadienyl derivative complexes containing heteroaromatic ligands”, J. Inorg. Biochem., 2011, 105, 241-249. DOI: 10.1016/j.jinorgbio.2010.10.009.

 3. M. Helena Garcia, Andreia Valente, Pedro Florindo, Tânia S. Morais, M. Fátima M. Piedade, M. Teresa Duarte, Virtudes Moreno, “New Ruthenium(II) Mixed Metallocene derived complexes: Synthesis, Characterization by X-ray Diffraction Studies and Evaluation on DNA interaction by Atomic Force Microcopy”, Inorg. Chim. Acta, 2010, 363, 3765- 3775. DOI: 10.1016/j.ica.2010.05.034.

 2. Virtudes Moreno, Julia Lorenzo, Francesc X. Avilés, M. Helena Garcia, João Ribeiro, Tânia S. Morais, Pedro Florindo, “Studies of the Antiproliferative Activity of Ruthenium(II) Cyclopentadienyl derived Complexes with Nitrogen Coordinated Ligands”, Bioinorg. Chem. App., 2010, article ID 936834. DOI: 10.1155/2010/396834.           

 1. M. Helena Garcia, Tânia S. Morais, Pedro Florindo, M. Fátima M. Piedade, Virtudes Moreno, Carlos Ciudad, Veronica Noe, “Inhibition of Cancer Cell Growth by Ruthenium(II) Cycplopentadienyl derivative Complexes with Heteroaromatic Ligands”, J. Inorg. Biochem., 2009, 103, 354-361. DOI: 10.1016/j.jinorgbio. 2008.11.016.